About clinical studiesPlay Video
Could you or someone you know take part in one of our Alzheimer’s disease clinical studies?
What are clinical studies?
- Clinical studies allow us to investigate the potential of medicine. They do this by testing on volunteers, but only after the investigational treatment in question has gone through extensive testing in the laboratory.
- All medications must be tested in clinical studies (also known as clinical research studies) before they are approved and available for use.
- Without people willing to volunteer their time for medical research, it would be almost impossible to evaluate new treatments for medical conditions, and potentially few medical advances would be made. Most clinical studies use a placebo to test the investigational medicine against the drug.
What is a placebo?
A placebo is something that looks exactly like the investigational medication, and is delivered in exactly the same way, but does not contain any active medication. Placebos help scientists to see whether any changes are due to the medication in question, or some other factor.
20-80 participants Studies the initial safety of an investigational medication Participants in Phase 1 studies are usually healthy volunteers
100-300 participants Studies the safety and initial efficacy of an investigational medication Participants in Phase 2 studies are usually patients with the condition On some occasions, large Phase 1 studies can replace Phase 2 studies
1000-3000 participants Studies the safety and efficacy of an investigational medication Phase 3 studies are essential for the drug to be approved
Thousands of participants Studies the use of approved medications in the real world
Note: This information is about clinical trials in general – it is not specific to ENGAGE and EMERGE. The safety of participants is always the first priority of any clinical study.
What being on a clinical study means
- Your health may be monitored more closely while you are on the study than it would normally.
- You may receive the investigational medication or you may receive a placebo.
- There is no guaranteed impact on the disease if you receive the investigational medication. It may make it better, worse or the same as before. There may also be no benefit from participating in a clinical study.
- You may provide valuable information that might help improve medical research and knowledge. This could benefit you, and others like you, in the future.
- You may experience unwanted side effects (these are listed in full in the informed consent form, although we can never predict them all).